CIA agent Court Gentry (Ryan Gosling), aka Sierra Six, was bailed out of a federal prison by his supervisor, Donald Fitzroy (Billy Bob Thornton). After 18 years of service, Gentry is one of the best assets authorized by the Agency, but the tables are turned and he becomes the target, pursued by Lloyd Hansen (Chris Evans), a former CIA partner of highly questionable methods. Agent Dani Miranda (Ana de Armas) ends up being an unexpected and necessary ally who will cover his back.