Set 25 years after the events of the original Bulletproof, the film returns to play the characters of Wayans and Sandler with Faizon Love (Friday) and Kirk Fox (Parks and Recreation). In the sequel, Jack (Faizon Love) now works as a Special Agent with the mission of ending a powerful South African criminal family. The officer reluctantly covers up again, this time taking the identity of Moses (Kirk Fox), the man who shot him in the head a quarter of a century ago and who has close ties to the case. Of course, everything goes crazy when the real Moses puts himself in danger without realizing it, and Jack and Moses must discover once again how to stay alive while trying to thwart the sinister plans of a high-profile criminal brain.